Priyanka Baloni

Bile Acids Provide More Evidence of the Gut Microbiome’s Effect on Alzheimer’s Disease

ISB researchers and their collaborators are looking beyond the one-drug, one-solution approach that has thus far failed in Alzheimer’s disease research. Instead, they are focusing on other promising research avenues, such as the possible role of the gut microbiome in dementia.

Bile Acids Provide More Evidence of the Gut Microbiome’s Effect on Alzheimer’s Disease
Bile Acids Provide More Evidence of the Gut Microbiome’s Effect on Alzheimer’s Disease
Overall composition of gut microbiome in participants

Variations in the Microbiome Associated with Health, Disease

ISB researchers examined the associations between the gut microbiomes of about 3,400 people and roughly 150 host characteristics. The team looked at diet, medication use, clinical blood markers, and other lifestyle and clinical factors, and found evidence that variations of the gut microbiome are associated with health and disease.

Variations in the Microbiome Associated with Health, Disease
Variations in the Microbiome Associated with Health, Disease
Dr. Andrew Magis

ISB Researchers Identify Signals of Metastatic Cancer Years Prior to Diagnosis

By analyzing blood plasma samples taken at several time points, ISB researchers have identified specific proteins that persistently presented as outliers and signaled metastatic cancer well before patients were diagnosed. The findings were published in the journal Scientific Reports.

ISB Researchers Identify Signals of Metastatic Cancer Years Prior to Diagnosis
ISB Researchers Identify Signals of Metastatic Cancer Years Prior to Diagnosis
Illustration depicting an individual's genetic risk for disease being "reflected."

ISB Researchers Show Genetic Risk for Disease Often Reflected in Our Blood

Diseases develop gradually over years, sometimes decades, before symptoms appear, and are due to malfunctioning physiological processes brought about by our genes and environment. In research published in the journal Proceedings of the National Academy of Sciences (PNAS), ISB researchers have shown how an individual’s genetic risk for disease is often reflected in their blood.

ISB Researchers Show Genetic Risk for Disease Often Reflected in Our Blood
ISB Researchers Show Genetic Risk for Disease Often Reflected in Our Blood
Bacterial tug of war between prevotella and bacteroides -- gut microbiome

It’s ‘Either/Or’ for Two Common Gut Microbiome Genera, and Switching Teams Is Tougher Than Expected

There is a dichotomy between Bacteroides- and Prevotella-dominated guts — two common gut bacterial genera — and there is a significant barrier when it comes to transitioning from one to the other.

It’s ‘Either/Or’ for Two Common Gut Microbiome Genera, and Switching Teams Is Tougher Than Expected
It’s ‘Either/Or’ for Two Common Gut Microbiome Genera, and Switching Teams Is Tougher Than Expected
soldier

ISB Researchers Seek a Better Way to Identify Chronic Mild Traumatic Brain Injury

Mild traumatic brain injury (mTBI) has been a frequent injury among U.S. combatants, and blast-related mTBI has been called the “signature injury” from military conflicts in Iraq and Afghanistan. ISB researchers are working to develop new methods to identify molecular changes in the blood of war veterans diagnosed with chronic mTBI.

ISB Researchers Seek a Better Way to Identify Chronic Mild Traumatic Brain Injury
ISB Researchers Seek a Better Way to Identify Chronic Mild Traumatic Brain Injury
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