Dr. Andrew Magis

ISB Researchers Identify Signals of Metastatic Cancer Years Prior to Diagnosis

By analyzing blood plasma samples taken at several time points, ISB researchers have identified specific proteins that persistently presented as outliers and signaled metastatic cancer well before patients were diagnosed. The findings were published in the journal Scientific Reports.

ISB Researchers Identify Signals of Metastatic Cancer Years Prior to Diagnosis
ISB Researchers Identify Signals of Metastatic Cancer Years Prior to Diagnosis
Illustration depicting an individual's genetic risk for disease being "reflected."

ISB Researchers Show Genetic Risk for Disease Often Reflected in Our Blood

Diseases develop gradually over years, sometimes decades, before symptoms appear, and are due to malfunctioning physiological processes brought about by our genes and environment. In research published in the journal Proceedings of the National Academy of Sciences (PNAS), ISB researchers have shown how an individual’s genetic risk for disease is often reflected in their blood.

ISB Researchers Show Genetic Risk for Disease Often Reflected in Our Blood
ISB Researchers Show Genetic Risk for Disease Often Reflected in Our Blood
Bacterial tug of war between prevotella and bacteroides -- gut microbiome

It’s ‘Either/Or’ for Two Common Gut Microbiome Genera, and Switching Teams Is Tougher Than Expected

There is a dichotomy between Bacteroides- and Prevotella-dominated guts -- two common gut bacterial genera -- and there is a significant barrier when it comes to transitioning from one to the other.

It’s ‘Either/Or’ for Two Common Gut Microbiome Genera, and Switching Teams Is Tougher Than Expected
It’s ‘Either/Or’ for Two Common Gut Microbiome Genera, and Switching Teams Is Tougher Than Expected
soldier

ISB Researchers Seek a Better Way to Identify Chronic Mild Traumatic Brain Injury

Mild traumatic brain injury (mTBI) has been a frequent injury among U.S. combatants, and blast-related mTBI has been called the “signature injury” from military conflicts in Iraq and Afghanistan. ISB researchers are working to develop new methods to identify molecular changes in the blood of war veterans diagnosed with chronic mTBI.

ISB Researchers Seek a Better Way to Identify Chronic Mild Traumatic Brain Injury
ISB Researchers Seek a Better Way to Identify Chronic Mild Traumatic Brain Injury
biological age thumbnail

How Old Are You? Your Body Might Disagree With That Answer

Researchers at ISB harnessed deep molecular and physiological information to determine an individual’s biological age, which they found was reflective of overall health compared to chronological age. The findings were published in the Journals of Gerontology: Series A.

How Old Are You? Your Body Might Disagree With That Answer
How Old Are You? Your Body Might Disagree With That Answer
graphic of molecules

Using Blood to Predict Gut Microbiome Diversity

Predicting the alpha diversity of an individual's gut microbiome is possible by examining metabolites in the blood. The robust relationship between host metabolome and gut microbiome diversity opens the door for a fast, cheap and reliable blood test to identify individuals with low gut diversity.

Using Blood to Predict Gut Microbiome Diversity
Using Blood to Predict Gut Microbiome Diversity
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