Kelsey Scherler

Kumari, S., Lausted, C., Scherler, K., Ng, A. H. C., Lu, Y., Lee, I., Hood, L., & Wang, K. (2024). Approaches and Challenges in Characterizing the Molecular Content of Extracellular Vesicles for Biomarker Discovery. Biomolecules, 14(12), 1599. https://doi.org/10.3390/biom14121599 Cite Download

Nguyen, K. T., Rima, X. Y., Nguyen, L. T. H., Wang, X., Kwak, K. J., Yoon, M. J., Li, H., Chiang, C.-L., Doon-Ralls, J., Scherler, K., Fallen, S., Godfrey, S. L., Wallick, J. A., Magaña, S. M., Palmer, A. F., Lee, I., Nunn, C. C., Reeves, K. M., Kaplan, H. G., … Reátegui, E. (2024). Integrated Antigenic and Nucleic Acid Detection in Single Virions and Extracellular Vesicles with Viral Content. Advanced Healthcare Materials, e2400622. https://doi.org/10.1002/adhm.202400622 Cite

Zhang, J., Rima, X. Y., Wang, X., Nguyen, L. T. H., Huntoon, K., Ma, Y., Palacio, P. L., Nguyen, K. T., Albert, K., Duong-Thi, M.-D., Walters, N., Kwak, K. J., Yoon, M. J., Li, H., Doon-Ralls, J., Hisey, C. L., Lee, D., Wang, Y., Ha, J., … Reátegui, E. (2023). Engineering a tunable micropattern-array assay to sort single extracellular vesicles and particles to detect RNA and protein in situ. Journal of Extracellular Vesicles, 12(11), e12369. https://doi.org/10.1002/jev2.12369 Cite Download

Ng, A. H. C., Hu, H., Wang, K., Scherler, K., Warren, S. E., Zollinger, D. R., McKay-Fleisch, J., Sorg, K., Beechem, J. M., Ragaglia, E., Lacy, J. M., Smith, K. D., Marshall, D. A., Bundesmann, M. M., López de Castilla, D., Corwin, D., Yarid, N., Knudsen, B. S., Lu, Y., … Heath, J. R. (2023). Organ-specific immunity: A tissue analysis framework for investigating local immune responses to SARS-CoV-2. Cell Reports, 42(10), 113212. https://doi.org/10.1016/j.celrep.2023.113212 Cite Download

Park, J., Fong Legaspi, S. L., Schwartzman, L. M., Gygli, S. M., Sheng, Z.-M., Freeman, A. D., Matthews, L. M., Xiao, Y., Ramuta, M. D., Batchenkova, N. A., Qi, L., Rosas, L. A., Williams, S. L., Scherler, K., Gouzoulis, M., Bellayr, I., Morens, D. M., Walters, K.-A., Memoli, M. J., … Taubenberger, J. K. (2022). An inactivated multivalent influenza A virus vaccine is broadly protective in mice and ferrets. Science Translational Medicine, 14(653), eabo2167. https://doi.org/10.1126/scitranslmed.abo2167 Cite Download

Su, Y., Yuan, D., Chen, D. G., Ng, R. H., Wang, K., Choi, J., Li, S., Hong, S., Zhang, R., Xie, J., Kornilov, S. A., Scherler, K., Pavlovitch-Bedzyk, A. J., Dong, S., Lausted, C., Lee, I., Fallen, S., Dai, C. L., Baloni, P., … Heath, J. R. (2022). Multiple Early Factors Anticipate Post-Acute COVID-19 Sequelae. Cell, 0(0). https://doi.org/10.1016/j.cell.2022.01.014 Cite Download

D’Agnillo, F., Walters, K. A., Xiao, Y., Sheng, Z.-M., Scherler, K., Park, J., Gygli, S., Rosas, L. A., Sadtler, K., Kalish, H., Blatti, C. A., Zhu, R., Gatzke, L., Bushell, C., Memoli, M. J., O’Day, S. J., Fischer, T. D., Hammond, T. C., Lee, R. C., … Taubenberger, J. K. (2021). Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19. Science Translational Medicine, 13(620), eabj7790. https://doi.org/10.1126/scitranslmed.abj7790 Cite Download

Giurgea, L. T., Cervantes-Medina, A., Walters, K. A., Scherler, K., Han, A., Czajkowski, L. M., Baus, H. A., Hunsberger, S., Klein, S. L., Kash, J. C., Taubenberger, J. K., & Memoli, M. J. (2021). Sex Differences in Influenza: The Challenge Study Experience. The Journal of Infectious Diseases, jiab422. https://doi.org/10.1093/infdis/jiab422 Cite Download

Giurgea, L. T., Park, J.-K., Walters, K. A., Scherler, K., Cervantes-Medina, A., Freeman, A., Rosas, L. A., Kash, J. C., Taubenberger, J. K., & Memoli, M. J. (2021). The effect of calcium and magnesium on activity, immunogenicity, and efficacy of a recombinant N1/N2 neuraminidase vaccine. NPJ Vaccines, 6(1), 48. https://doi.org/10.1038/s41541-021-00310-x Cite Download

Su, Y., Yuan, D., Chen, D. G., Wang, K., Choi, J., Dai, C. L., Hong, S., Zhang, R., Xie, J., Li, S., Scherler, K., Pavlovitch-Bedzyk, A. J., Dong, S., Lausted, C., Ng, R. H., Lee, I., Fallen, S., Kornilov, S. A., Baloni, P., … Heath, J. R. (2021). Heterogeneous immunological recovery trajectories revealed in post-acute COVID-19. MedRxiv, 2021.03.19.21254004. https://doi.org/10.1101/2021.03.19.21254004 Cite Download

Ghai, V., Fallen, S., Baxter, D., Scherler, K., Kim, T.-K., Zhou, Y., Meabon, J. S., Logsdon, A. F., Banks, W. A., Schindler, A. G., Cook, D. G., Peskind, E. R., Lee, I., & Wang, K. (2020). Alterations in Plasma microRNA and Protein Levels in War Veterans with Chronic Mild Traumatic Brain Injury. Journal of Neurotrauma. https://doi.org/10.1089/neu.2019.6826 Cite

Park, J.-K., Xiao, Y., Ramuta, M. D., Rosas, L. A., Fong, S., Matthews, A. M., Freeman, A. D., Gouzoulis, M. A., Batchenkova, N. A., Yang, X., Scherler, K., Qi, L., Reed, S., Athota, R., Czajkowski, L., Han, A., Morens, D. M., Walters, K. A., Memoli, M. J., … Taubenberger, J. K. (2020). Pre-existing immunity to influenza virus hemagglutinin stalk might drive selection for antibody-escape mutant viruses in a human challenge model. Nature Medicine, 26(8), 1240–1246. https://doi.org/10.1038/s41591-020-0937-x Cite Download

Su, Y., Chen, D., Yuan, D., Lausted, C., Choi, J., Dai, C. L., Voillet, V., Duvvuri, V. R., Scherler, K., Troisch, P., Baloni, P., Qin, G., Smith, B., Kornilov, S. A., Rostomily, C., Xu, A., Li, J., Dong, S., Rothchild, A., … Heath, J. R. (2020). Multi-omics resolves a sharp disease-state shift between mild and moderate COVID-19. Cell, S0092867420314446. https://doi.org/10.1016/j.cell.2020.10.037 Cite Download

Walters, K. A., Zhu, R., Welge, M., Scherler, K., Park, J.-K., Rahil, Z., Wang, H., Auvil, L., Bushell, C., Lee, M. Y., Baxter, D., Bristol, T., Rosas, L. A., Cervantes-Medina, A., Czajkowski, L., Han, A., Memoli, M. J., Taubenberger, J. K., & Kash, J. C. (2019). Differential Effects of Influenza Virus NA, HA Head, and HA Stalk Antibodies on Peripheral Blood Leukocyte Gene Expression during Human Infection. MBio, 10(3). https://doi.org/10.1128/mBio.00760-19 Cite Download

Lee, M.-J., Fallen, S., Zhou, Y., Baxter, D., Scherler, K., Kuo, M.-F., & Wang, K. (2019). The Impact of Moyamoya Disease and RNF213 Mutations on the Spectrum of Plasma Protein and MicroRNA. Journal of Clinical Medicine, 8(10). https://doi.org/10.3390/jcm8101648 Cite Download

Lee, M. Y., Baxter, D., Scherler, K., Kim, T.-K., Wu, X., Abu-Amara, D., Flory, J., Yehuda, R., Marmar, C., Jett, M., Lee, I., Wang, K., & Hood, L. (2019). Distinct Profiles of Cell-Free MicroRNAs in Plasma of Veterans with Post-Traumatic Stress Disorder. Journal of Clinical Medicine, 8(7). https://doi.org/10.3390/jcm8070963 Cite Download

Fallen, S., Baxter, D., Wu, X., Kim, T.-K., Shynlova, O., Lee, M. Y., Scherler, K., Lye, S., Hood, L., & Wang, K. (2018). Extracellular vesicle RNAs reflect placenta dysfunction and are a biomarker source for preterm labour. Journal of Cellular and Molecular Medicine. https://doi.org/10.1111/jcmm.13570 Cite

Kash, J. C., Walters, K. A., Kindrachuk, J., Baxter, D., Scherler, K., Janosko, K. B., Adams, R. D., Herbert, A. S., James, R. M., Stonier, S. W., Memoli, M. J., Dye, J. M., Davey, R. T., Chertow, D. S., & Taubenberger, J. K. (2017). Longitudinal peripheral blood transcriptional analysis of a patient with severe Ebola virus disease. Science Translational Medicine, 9(385). https://doi.org/10.1126/scitranslmed.aai9321 Cite

Ament, S. A., Pearl, J. R., Grindeland, A., St Claire, J., Earls, J. C., Kovalenko, M., Gillis, T., Mysore, J., Gusella, J. F., Lee, J.-M., Kwak, S., Howland, D., Lee, M. Y., Baxter, D., Scherler, K., Wang, K., Geman, D., Carroll, J. B., MacDonald, M. E., … Hood, L. E. (2017). High resolution time-course mapping of early transcriptomic, molecular and cellular phenotypes in Huntington’s disease CAG knock-in mice across multiple genetic backgrounds. Human Molecular Genetics, 26(5), 913–922. https://doi.org/10.1093/hmg/ddx006 Cite

Wu, X., Kim, T.-K., Baxter, D., Scherler, K., Gordon, A., Fong, O., Etheridge, A., Galas, D. J., & Wang, K. (2017). sRNAnalyzer-a flexible and customizable small RNA sequencing data analysis pipeline. Nucleic Acids Research. https://doi.org/10.1093/nar/gkx999 Cite

Lee, I., Baxter, D., Lee, M. Y., Scherler, K., & Wang, K. (2016). The Importance of Standardization on Analyzing Circulating RNA. Molecular Diagnosis & Therapy. https://doi.org/10.1007/s40291-016-0251-y Cite

Wu, S., Kim, T.-K., Wu, X., Scherler, K., Baxter, D., Wang, K., Krasnow, R. E., Reed, T., & Dai, J. (2016). Circulating MicroRNAs and Life Expectancy Among Identical Twins. Annals of Human Genetics, 80(5), 247–256. https://doi.org/10.1111/ahg.12160 Cite

Cho, J. H., Lee, I., Hammamieh, R., Wang, K., Baxter, D., Scherler, K., Etheridge, A., Kulchenko, A., Gautam, A., Muhie, S., Chakraborty, N., Galas, D. J., Jett, M., & Hood, L. (2014). Molecular evidence of stress-induced acute heart injury in a mouse model simulating posttraumatic stress disorder. Proceedings of the National Academy of Sciences of the United States of America, 111(8), 3188–3193. Cite

Qi, L., Pujanauski, L. M., Davis, A. S., Schwartzman, L. M., Chertow, D. S., Baxter, D., Scherler, K., Hartshorn, K. L., Slemons, R. D., Walters, K. A., Kash, J. C., & Taubenberger, J. K. (2014). Contemporary avian influenza A virus subtype H1, H6, H7, H10, and H15 hemagglutinin genes encode a mammalian virulence factor similar to the 1918 pandemic virus H1 hemagglutinin. MBio, 5(6), e02116. https://doi.org/10.1128/mBio.02116-14 Cite