Kelsey Scherler

Research Associate

Virology

Kelsey Scherler currently works at the Institute for Systems Biology. Kelsey does research in Microbiology, Immunology and Virology.

Qi, Li, Lindsey M. Pujanauski, A. Sally Davis, Louis M. Schwartzman, Daniel S. Chertow, David Baxter, Kelsey Scherler, et al. 2014. “Contemporary Avian Influenza A Virus Subtype H1, H6, H7, H10, and H15 Hemagglutinin Genes Encode a Mammalian Virulence Factor Similar to the 1918 Pandemic Virus H1 Hemagglutinin.” MBio 5 (6): e02116. https://doi.org/10.1128/mBio.02116-14. Cite
Cho, J. H., I. Lee, R. Hammamieh, K. Wang, D. Baxter, K. Scherler, A. Etheridge, et al. 2014. “Molecular Evidence of Stress-Induced Acute Heart Injury in a Mouse Model Simulating Posttraumatic Stress Disorder.” Proceedings of the National Academy of Sciences of the United States of America 111 (8): 3188–93. Cite
Wu, Shenghui, Taek-Kyun Kim, Xiaogang Wu, Kelsey Scherler, David Baxter, Kai Wang, Ruth E. Krasnow, Terry Reed, and Jun Dai. 2016. “Circulating MicroRNAs and Life Expectancy Among Identical Twins.” Annals of Human Genetics 80 (5): 247–56. https://doi.org/10.1111/ahg.12160. Cite
Lee, Inyoul, David Baxter, Min Young Lee, Kelsey Scherler, and Kai Wang. 2016. “The Importance of Standardization on Analyzing Circulating RNA.” Molecular Diagnosis & Therapy. https://doi.org/10.1007/s40291-016-0251-y. Cite
Wu, Xiaogang, Taek-Kyun Kim, David Baxter, Kelsey Scherler, Aaron Gordon, Olivia Fong, Alton Etheridge, David J. Galas, and Kai Wang. 2017. “SRNAnalyzer-a Flexible and Customizable Small RNA Sequencing Data Analysis Pipeline.” Nucleic Acids Research. https://doi.org/10.1093/nar/gkx999. Cite
Ament, Seth A., Jocelynn R. Pearl, Andrea Grindeland, Jason St Claire, John C. Earls, Marina Kovalenko, Tammy Gillis, et al. 2017. “High Resolution Time-Course Mapping of Early Transcriptomic, Molecular and Cellular Phenotypes in Huntington’s Disease CAG Knock-in Mice across Multiple Genetic Backgrounds.” Human Molecular Genetics 26 (5): 913–22. https://doi.org/10.1093/hmg/ddx006. Cite
Kash, John C., K.A. Walters, Jason Kindrachuk, David Baxter, Kelsey Scherler, Krisztina B. Janosko, Rick D. Adams, et al. 2017. “Longitudinal Peripheral Blood Transcriptional Analysis of a Patient with Severe Ebola Virus Disease.” Science Translational Medicine 9 (385). https://doi.org/10.1126/scitranslmed.aai9321. Cite
Fallen, Shannon, David Baxter, Xiaogang Wu, Taek-Kyun Kim, Oksana Shynlova, Min Young Lee, Kelsey Scherler, Stephen Lye, Leroy Hood, and Kai Wang. 2018. “Extracellular Vesicle RNAs Reflect Placenta Dysfunction and Are a Biomarker Source for Preterm Labour.” Journal of Cellular and Molecular Medicine. https://doi.org/10.1111/jcmm.13570. Cite
Lee, Min Young, David Baxter, Kelsey Scherler, Taek-Kyun Kim, Xiaogang Wu, Duna Abu-Amara, Janine Flory, et al. 2019. “Distinct Profiles of Cell-Free MicroRNAs in Plasma of Veterans with Post-Traumatic Stress Disorder.” Journal of Clinical Medicine 8 (7). https://doi.org/10.3390/jcm8070963. Cite Download
Lee, Ming-Jen, Shannon Fallen, Yong Zhou, David Baxter, Kelsey Scherler, Meng-Fai Kuo, and Kai Wang. 2019. “The Impact of Moyamoya Disease and RNF213 Mutations on the Spectrum of Plasma Protein and MicroRNA.” Journal of Clinical Medicine 8 (10). https://doi.org/10.3390/jcm8101648. Cite Download
Walters, K.A., Ruoqing Zhu, Michael Welge, Kelsey Scherler, Jae-Keun Park, Zainab Rahil, Hao Wang, et al. 2019. “Differential Effects of Influenza Virus NA, HA Head, and HA Stalk Antibodies on Peripheral Blood Leukocyte Gene Expression during Human Infection.” MBio 10 (3). https://doi.org/10.1128/mBio.00760-19. Cite Download
Su, Yapeng, Daniel Chen, Dan Yuan, Christopher Lausted, Jongchan Choi, Chengzhen L. Dai, Valentin Voillet, et al. 2020. “Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19.” Cell, S0092867420314446. https://doi.org/10.1016/j.cell.2020.10.037. Cite Download
Park, Jae-Keun, Yongli Xiao, Mitchell D. Ramuta, Luz Angela Rosas, Sharon Fong, Alexis M. Matthews, Ashley D. Freeman, et al. 2020. “Pre-Existing Immunity to Influenza Virus Hemagglutinin Stalk Might Drive Selection for Antibody-Escape Mutant Viruses in a Human Challenge Model.” Nature Medicine 26 (8): 1240–46. https://doi.org/10.1038/s41591-020-0937-x. Cite Download
Ghai, Vikas, Shannon Fallen, David Baxter, Kelsey Scherler, Taek-Kyun Kim, Yong Zhou, James S. Meabon, et al. 2020. “Alterations in Plasma MicroRNA and Protein Levels in War Veterans with Chronic Mild Traumatic Brain Injury.” Journal of Neurotrauma. https://doi.org/10.1089/neu.2019.6826. Cite
Su, Yapeng, Dan Yuan, Daniel G. Chen, Kai Wang, Jongchan Choi, Chengzhen L. Dai, Sunga Hong, et al. 2021. “Heterogeneous Immunological Recovery Trajectories Revealed in Post-Acute COVID-19.” MedRxiv, 2021.03.19.21254004. https://doi.org/10.1101/2021.03.19.21254004. Cite Download
Giurgea, Luca T., Jae-Keun Park, K.A. Walters, Kelsey Scherler, Adriana Cervantes-Medina, Ashley Freeman, Luz Angela Rosas, John C. Kash, Jeffery K. Taubenberger, and Matthew J. Memoli. 2021. “The Effect of Calcium and Magnesium on Activity, Immunogenicity, and Efficacy of a Recombinant N1/N2 Neuraminidase Vaccine.” NPJ Vaccines 6 (1): 48. https://doi.org/10.1038/s41541-021-00310-x. Cite Download
Giurgea, Luca T., Adriana Cervantes-Medina, K.A. Walters, Kelsey Scherler, Alison Han, Lindsay M. Czajkowski, Holly Ann Baus, et al. 2021. “Sex Differences in Influenza: The Challenge Study Experience.” The Journal of Infectious Diseases, jiab422. https://doi.org/10.1093/infdis/jiab422. Cite Download
D’Agnillo, Felice, K.A. Walters, Yongli Xiao, Zong-Mei Sheng, Kelsey Scherler, Jaekeun Park, Sebastian Gygli, et al. 2021. “Lung Epithelial and Endothelial Damage, Loss of Tissue Repair, Inhibition of Fibrinolysis, and Cellular Senescence in Fatal COVID-19.” Science Translational Medicine 13 (620): eabj7790. https://doi.org/10.1126/scitranslmed.abj7790. Cite Download
Su, Yapeng, Dan Yuan, Daniel G. Chen, Rachel H. Ng, Kai Wang, Jongchan Choi, Sarah Li, et al. 2022. “Multiple Early Factors Anticipate Post-Acute COVID-19 Sequelae.” Cell 0 (0). https://doi.org/10.1016/j.cell.2022.01.014. Cite Download
Park, Jaekeun, Sharon L. Fong Legaspi, Louis M. Schwartzman, Sebastian M. Gygli, Zhong-Mei Sheng, Ashley D. Freeman, Lex M. Matthews, et al. 2022. “An Inactivated Multivalent Influenza A Virus Vaccine Is Broadly Protective in Mice and Ferrets.” Science Translational Medicine 14 (653): eabo2167. https://doi.org/10.1126/scitranslmed.abo2167. Cite Download
Ng, Alphonsus H. C., Huiqian Hu, Kai Wang, Kelsey Scherler, Sarah E. Warren, Daniel R. Zollinger, Jill McKay-Fleisch, et al. 2023. “Organ-Specific Immunity: A Tissue Analysis Framework for Investigating Local Immune Responses to SARS-CoV-2.” Cell Reports 42 (10): 113212. https://doi.org/10.1016/j.celrep.2023.113212. Cite Download
Zhang, Jingjing, Xilal Y. Rima, Xinyu Wang, Luong T. H. Nguyen, Kristin Huntoon, Yifan Ma, Paola Loreto Palacio, et al. 2023. “Engineering a Tunable Micropattern-Array Assay to Sort Single Extracellular Vesicles and Particles to Detect RNA and Protein in Situ.” Journal of Extracellular Vesicles 12 (11): e12369. https://doi.org/10.1002/jev2.12369. Cite Download
Nguyen, Kim Truc, Xilal Y. Rima, Luong T. H. Nguyen, Xinyu Wang, Kwang Joo Kwak, Min Jin Yoon, Hong Li, et al. 2024. “Integrated Antigenic and Nucleic Acid Detection in Single Virions and Extracellular Vesicles with Viral Content.” Advanced Healthcare Materials, e2400622. https://doi.org/10.1002/adhm.202400622. Cite