Illustration depicting an individual's genetic risk for disease being "reflected."

ISB Researchers Show Genetic Risk for Disease Often Reflected in Our Blood

Diseases develop gradually over years, sometimes decades, before symptoms appear, and are due to malfunctioning physiological processes brought about by our genes and environment. In research published in the journal Proceedings of the National Academy of Sciences (PNAS), ISB researchers have shown how an individual’s genetic risk for disease is often reflected in their blood.

ISB Researchers Show Genetic Risk for Disease Often Reflected in Our Blood
ISB Researchers Show Genetic Risk for Disease Often Reflected in Our Blood
Bacterial tug of war between prevotella and bacteroides -- gut microbiome

It’s ‘Either/Or’ for Two Common Gut Microbiome Genera, and Switching Teams Is Tougher Than Expected

There is a dichotomy between Bacteroides- and Prevotella-dominated guts -- two common gut bacterial genera -- and there is a significant barrier when it comes to transitioning from one to the other.

It’s ‘Either/Or’ for Two Common Gut Microbiome Genera, and Switching Teams Is Tougher Than Expected
It’s ‘Either/Or’ for Two Common Gut Microbiome Genera, and Switching Teams Is Tougher Than Expected
biological age thumbnail

How Old Are You? Your Body Might Disagree With That Answer

Researchers at ISB harnessed deep molecular and physiological information to determine an individual’s biological age, which they found was reflective of overall health compared to chronological age. The findings were published in the Journals of Gerontology: Series A.

How Old Are You? Your Body Might Disagree With That Answer
How Old Are You? Your Body Might Disagree With That Answer
graphic of molecules

Using Blood to Predict Gut Microbiome Diversity

Predicting the alpha diversity of an individual's gut microbiome is possible by examining metabolites in the blood. The robust relationship between host metabolome and gut microbiome diversity opens the door for a fast, cheap and reliable blood test to identify individuals with low gut diversity.

Using Blood to Predict Gut Microbiome Diversity
Using Blood to Predict Gut Microbiome Diversity
two people holding hands

Clinical Trial Explores the Effects of Health Coaching on Cognitive Function in Patients with Early-Stage Alzheimer’s

Institute for Systems Biology (ISB) is among several organizations conducting a clinical trial testing how health coaching affects the cognitive function of patients with early-stage Alzheimer’s disease and analyzing longitudinal, multi-omic data to explore transitions in cognitive function over time.

Clinical Trial Explores the Effects of Health Coaching on Cognitive Function in Patients with Early-Stage Alzheimer’s
Clinical Trial Explores the Effects of Health Coaching on Cognitive Function in Patients with Early-Stage Alzheimer’s
1 3 4 5 6